Genetics
Oxford Biosystems Cadama (OBC) is proud to represent a variety of international companies who supply us with systems for genetic testing in clinical and research laboratories.
As the diagnostic testing market in the UK continues to evolve and change, so we try to respond by offering a range of products for conventional methods as well as newer molecular technologies.
AmnioMed® Smart
The latest arrival from EuroClone Life Sciences. AmnioMed® Smart is a high quality medium that is optimised for primary cultures of amniocytes and chorionic villus samples (CVS). Suitable for open and closed culture, ready-to use and guaranteed growth in 7-9 days
ChromoLympho B
ChromoLympho B is a “new generation” proliferation reagent that is designed for use in culturing peripheral blood/bone marrow cells from patients affected with chronic lymphocytic leukaemia (CLL) and other B-cell lymphoproliferative syndromes. It has been shown to improve the success rate of metaphase analysis and more importantly, gives an impressive abnormality rate, similar to Fish analysis findings.
AmnioFlask®
AmnioFlask is a flask ultrasonically welded to a polystyrene microscope slide. The screw cap garantees a liquid and gas tight seal to prevent contamination and leakage during flask handling. At the end of the in situ culture the flask is easily removed from the slide.
AmnioChamber®
A polystyrene chamber with cover, sealed with a silicone gasket to a “sand blasted” microscope glass slide. When the in situ culture is complete the chamber and the gasket can be easily removed from the slide.
AmnioChamberSF®
A polystyrene chamber with cover, sealed with a strong biocompatible glue to a SuperFrost® microscope glass slide. At the end of the in situ culture the chamber is removed from the slide.
MaestroGen
MaestroNano
The cost-effective way to bring low volume DNA measurements to your lab. The MaestroNano will provide you with accurate measurements on DNA samples of 2µL volume but at half the price of our competitors.
MaestroSafe
A non-toxic alternative to Ethidium Bromide as a stain for nucleic acids.
MaestroSafe can be used in exactly the same way as Ethidium Bromide, by incorporating it into your agarose gel, or it can be used as a loading dye in pre-cast gels.
Either way, it is safe to handle and can be disposed off in normal waste, saving you money on waste disposal costs.
Focus 3M™ Integrated Cycler
Raise the real-time bar in your lab by switching to the Focus 3M™ Integrated Cycler. Very small, very quick, very easy and very flexible. Primers are available now for mutant and wild type factor V Leiden, Prothrombin, MTHFR 677 and MTHFR 1298.
Ask us for a demonstration and you will not be disappointed!
Karyotyping and Spectral Karyotyping Image analysis systems
Applied Spectral Imaging is a leading manufacturer of image capture and analysis software packages for karyotyping, FISH analysis and Spectral karyotyping. ASI’s systems are easy to use and highly versatile, making them suitable for the research as well as routine clinical use. Their HISKY system makes karyotyping of human, mouse and rodent samples extremely easy and efficient.
Contact us to arrange a demonstration or to find out about karyotyping services that are available.
DNA extraction from paraffin embedded tissue
Trimgen manufacture a great range of molecular biology reagents and kits, from buccal swabs to sequencing kits. One of the most popular being their WaxFree DNA kits for extraction of DNA from histology sections embedded in paraffin wax.
Also, popular are their Mutector kits for KRAS, EGFR, BRAF and their real-time PCR kit for warfarin sensitivity genotypng.
Genetic markers
We have a range of PCR based assays for the following Genetic Markers:
| ACE |
GST-P1 |
| Aldolase B |
HFE (C282Y/ H63D/ S65C) |
| alpha1 Antitrypsin (S/Z) |
HLA DQ-2 |
| ApoB100 |
HLA-B27 |
| ApoE |
HLA-DQ & DR4 |
| BRAF |
HLA-DQ 2+8 |
| CETP |
HLA-DRB1 Shared Epitope |
| Collagen (AS) |
KRAS |
| COMT |
Laktase |
| CYP1A1 |
MTHFR |
| CYP1A2 |
NAT2 |
| CYP2C19 |
Osteoporosis |
| CYP2C8 |
OxStress I (eNOS/ NAD(P)H Oxidase) |
| CYP2C9 |
OxStress II (SOD2/ Catalase) |
| CYP2E1 |
Parodontitis |
| Cystic Fibrosis |
PI3KCA |
| DPD |
r-Calcitonin |
| EGFR |
r-Estrogen |
| Factor II (Prothrombin) |
r-Vitamin D3 |
| Factor V |
SMN |
| FSME |
SRB |
| GST-M1/T1 |
UGT1A1 |
Contact us for further information.