Chemerin, an 18 kDa protein and a natural ligand of GPCR Chemokine-like Receptor 1, acts as both an adipokine involved in adipocyte differentiation and a chemoattractant in the recruitment of immune response cells.
ELISA kits for human use are available.
IGF-1 serum concentration is the main parameter in growth diagnostics. Critical for correct interprepation of measured IGF-1 values is the consideration of age-dependancy of IGF-1 concentration (with a peak at adolescence).
We supply different ELISA & RIA IGF-1 kits, offering various sensitivities, ranges, and sample requirements.
GLP-1 & GLP-2 ELISA
The glucagon-like peptides GLP-1 and GLP-2 are important gut hormones released from the small intestine upon nutrient ingestion. GLP-2 has been shown to play important roles in the regulation of gastrointestinal functions (digestion, absorption, motility, epithelial growth, and blood flow) and bone resorption.
ELISA kits for GLP-1, 2, active form and receptor are available for human, mouse and rat.
We supply a (serum & plasma) dedicated sample extraction systems (KT910) from Epitope Diagnostics for use with the GLP-1 (7-36) specific ELISA (KT871) and GLP-1 total ELISA (KT876).
For more information on available Glucagon-like peptide kits please use the product search box or contact us to discuss your requirements.
Insulin is the principal hormone responsible for the control of glucose metabolism. ELISA kits for H-type, S-type, U-type, are available, across various species. We also supply RIA kits and high sensitivity assays.
Please use our product search box for individual kit details.
Retinol Binding Protein
Retinol-binding protein (RBP)/RBP4 seems to play a key role in the development of insulin resistance. The fat cell derived peptide RBP/RBP4 also modulates the glucose homeostasis and impairs the insulin sensitivity as well as insulin resistance. The elevation of serum RBP/RBP4 causes systemic insulin resistance, whereas its reduction improves the insulin action.
CE marked ELISA kits are available.
The measurement of urinary proteins in the urine allows the diagnosis of proteinuria. In case of a microalbuminuria (selective proteinuria) increased levels ( > 150 mg protein/24h) of albumin and transferrin (marker proteins of the tubulus) could be measured. In case of severe diseases of the kidney with pathological changes of the basal membrane in the glomerulus (Chronic Glomerulonephritis, Tubulopathy, Nephrotic Syndrom) the protein level will rise up to > 3 g/24h and also the proteintyp will change to high molecular proteins like β-Lipoproteins and α 2-Macroglobulin (non-selective proteinuria).
Additionally previous investigations have shown that the determination of the two acute-phase proteins in the urines, C-reactive protein (CRP) and α 2-Macroglobulin, allows a noninvasive diagnosis of acute renal transplant dysfunction and rejection.
ELISA kits for human, mouse and rat are available.
Fetuin-A, also known as alpha-2-HS glycoprotein, is synthesized by the liver and secreted into blood stream. Fetuin-A occurs in high serum concentration during fetal life and involves in protease inhibitory activities and development-associated regulation of calcium metabolism and osteogenesis. It accumulates in bones and teeth as a major fraction of noncollagenous bone proteins.
Biologically, studies have demonstrated that Fetuin-A is the major calcification inhibitor found in serum, where it interferes with calcium salt precipitation.
Available as an ELISA for human diagnosis.
Proinsulin is the precursor of insulin and C-peptide and is made by the beta cells of the pancreas.
We have kits available for human, mouse and rat that will measure the intact form of human proinsulin.
Leptin is synthesized in adipocytes as a 16 kDa molecule and the circulating level is directly proportional to the total amount of fat in the body. The relaxin-like peptide family belongs in the insulin superfamily and consists of 7 peptides of high structural but low sequence similarity. In males, relaxin enhances motility of sperm in semen. In females relaxin is produced mainly by the corpus luteum, in both pregnant and nonpregnant females.
Elisa kits are available for human, mouse and rat and for measuring the clinical range and the receptor.